A Candidate Gene Study Revealed Sex-Specific Association Between the OLR1 Gene and Carotid Plaque

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A candidate gene study revealed sex-specific association between the OLR1 gene and carotid plaque.

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Clinical Sciences A Candidate Gene Study Revealed Sex-Specific Association Between the OLR1 Gene and Carotid Plaque

Background and Purpose—Sex differences have been recognized in stroke risk; however, the sex-dependent genetic contribution to stroke is unclear. We sought to examine the sex-dependent associations between genes involved in lipid metabolism and carotid atherosclerotic plaque, a subclinical precursor of stroke. Methods—For the Genetic Determinant of Subclinical Carotid Disease study, 287 Dominic...

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ژورنال

عنوان ژورنال: Stroke

سال: 2011

ISSN: 0039-2499,1524-4628

DOI: 10.1161/strokeaha.110.596841